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Frequently asked questions

Our Scientific Applications Support team has assembled a list of frequently asked questions to help you find answers quickly. Filter using one or more categories to focus on specific topics, or use the search bar to perform a text search.

What are AMOs (miRNA inhibitors) and how are they used?

Anti-microRNA Oligonucleotides (AMOs), or microRNA inhibitors, are steric blocking antisense reagents that inhibit microRNA (miRNA) function by hybridizing to and repressing the activity of a mature miRNA. The miRNA regulatory networks exert some level of control in the majority of cellular biological processes, including cell differentiation, apoptosis, and proliferation. AMOs/microRNA inhibitors can be used to inhibit miRNA function, both to investigate that function and for therapeutic purposes to correct diseases associated with miRNA dysregulation. You can read more about as well as order IDT® miRNA Inhibitors at miRNA Inhibitor product page.


*RUO—For research use only. Not for use in diagnostic procedures. Unless otherwise agreed to in writing, IDT does not intend for these products to be used in clinical applications and does not warrant their fitness or suitability for any clinical diagnostic use. Purchaser is solely responsible for all decisions regarding the use of these products and any associated regulatory or legal obligations.