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Megamer™ Single-Stranded DNA (ssDNA) Fragments

High-fidelity single-stranded DNA (ssDNA) fragments designed for your homology-directed repair (HDR) of CRISPR-mediated genome editing, in vitro transcription, and more.

Megamer Single-Stranded DNA Fragments (paired)

Includes your ssDNA fragment of interest and the complementary strand, delivered dry in separate tubes. Fragments are normalized to 3 µg final yield. Both strands will be delivered for each sequence entry.

Megamer™ ssDNA Fragments—Sense + Antisense, 201–500 bases$820.00 USD
Megamer™ ssDNA Fragments—Sense + Antisense, >500 bases$1.70 USD / base

Megamer Single-Stranded DNA Fragments (individual)

Includes your ssDNA fragment of interest, without the complementary strand, delivered dry. Fragments are normalized to 3 µg final yield.

Megamer™ ssDNA Fragment, 201–500 bases$615.00 USD
Megamer™ ssDNA Fragment, >500 bases$1.40 USD / base

Product details

Megamer ssDNA Fragments are single-stranded genomic blocks for research applications such as homology-directed repair of CRISPR-mediated genome editing, in vitro transcription, and more. Megamer fragments are 201–2000 bases in length and are generated from clonally derived DNA. Megamer ssDNA Fragments are sequence-verified via next generation sequencing and are typically shipped within 20 business days*. They are composed of A, T, G, and C nucleotides only.

* The time required to manufacture a Megamer ssDNA Fragment is dependent on many factors and may exceed the estimated delivery time.


Frequently asked questions


Sequence Information is secure and confidential at IDT. Please see our Confidentiality Statement for more information. All online ordering steps, including sequence entry and your choice of parameters, are also secure and protected.

We screen the sequence of every gene, gene fragment, and Megamer™ ssDNA fragment order we receive to (1) identify any regulated and other potentially dangerous pathogen sequences, and (2) verify that IDT’s gene customers are legitimate scientists engaged in beneficial research.

IDT is among the five founding members of the International Gene Synthesis Consortium (IGSC) and helped to create the IGSC’s Harmonized Screening Protocol. The Harmonized Screening Protocol describes the gene sequence and customer screening practices that IGSC member companies employ to prevent the misuse of synthetic genes. IDT takes the steps set out in the Harmonized Screening Protocol to screen the sequences of ordered genes and the prospective customers who submit those orders.

For more information about the IGSC and the Harmonized Screening Protocol, please visit the website at


In October 2010, the United States government issued final Screening Framework Guidance for Providers of Synthetic Double-Stranded DNA, describing how commercial providers of synthetic genes should perform gene sequence and customer screening. IDT and the other IGSC member companies supported the adoption of the Screening Framework Guidance, and IDT follows that Guidance in its application of the Harmonized Screening Protocol. For more information, please see 75 FR 62820 (Oct. 13, 2010), or

*RUO—For research use only. Not for use in diagnostic procedures. Unless otherwise agreed to in writing, IDT does not intend for these products to be used in clinical applications and does not warrant their fitness or suitability for any clinical diagnostic use. Purchaser is solely responsible for all decisions regarding the use of these products and any associated regulatory or legal obligations.