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CRISPR-Cas12a (Cpf1) genome editing

Expand your options for genome editing with the Alt-R® CRISPR-Cas12a System.

The Alt-R CRISPR-Cas12a System allows targeting of alternative sites that are not available to the CRISPR-Cas9 System and produces a staggered cut with a 5′ overhang.

  • Enables genome editing in organisms with AT-rich genomes
  • Allows interrogation of additional genomic regions compared to Cas9
  • Requires simple complexing of crRNA with the Cas12a protein—no tracrRNA needed
  • Permits efficient delivery of the RNP into cells by electroporation