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Why should I consider purification of my oligos?
Purification removes truncated products and other synthesis impurities. Our experience has shown that purifying an oligonucleotide that will be used in demanding applications saves both time and money in the long run. We recommend considering additional purification for any oligonucleotide that is to be used for an application other than routine PCR or DNA sequencing. As a general rule, IDT also recommends that any oligonucleotide longer than 40 bases should receive further purification.